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Situations such as fasting, malnutrition, the concomitant use of alcohol, and advanced age can be predisposing factors to hepatotoxicity.10,29 PP is the main cause of ALF worldwide, but the mortality rate is low, compared with other causes
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Initial treatment may involve frequent injections followed by maintenance regimens, with periodic review of symptoms and, where appropriate, blood counts
Analysis of time course and dose effect from metformin on body mass index in children and adolescents
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